TAGMe ndi chiyani
Padziko lonse lapansi: Tumor Aligned General Methylated Epiprobe (TAGMe)
Potsimikizira zitsanzo zachipatala zoposa 3000, mlingo wa methylation wa TAGMe m'matumbo a chotupa unali wapamwamba kwambiri kuposa wamtundu wamba.Chifukwa chake, TAGMe itha kugwiritsidwa ntchito ngati cholembera cha khansa ya pan-cancer pozindikira makhansa osiyanasiyana.
Majini okhudzana ndi histone ali ndi hypermethylated mu khansa ya m'mapapo ndipo hypermethylated HIST1H4F imatha kukhala ngati biomarker ya pan-cancer.
————Kafukufuku wa Khansa, NGATI:12.7
Detection performance
Monga cholembera cha khansa ya pan-cancer, TAGMe ili ndi kutsimikizika kwakukulu komanso chidwi pakutsimikizira zitsanzo zachipatala, zomwe zili ndi tanthauzo lofunikira pakuzindikiritsa zotupa.
TAGMe imakhudzidwa muzotupa zosiyanasiyana zotupa pomwe mawonekedwe ake ndi akulu kuposa 95%,