Njira yothetsera khansa endometrial, kuchotsa khansa pa siteji ya zotupa precancerous.Khansara ya endometrial ndi imodzi mwa khansa zazikulu zitatu zowopsa mu gynecology.
Khansara ya endometrial ndi imodzi mwa khansa yoopsa kwambiri mu ubereki wa amayi, yomwe ili yachiwiri pakati pa matenda a ubereki wa amayi ku China, ndipo imapezeka kwambiri mwa amayi akumidzi.Malinga ndi ziwerengero zochokera ku International Agency for Research on Cancer ya World Health Organisation, panali pafupifupi 420,000 odwala khansa ya endometrial padziko lonse lapansi mu 2020, ndipo pafupifupi 100,000 afa.
Mwa milanduyi, pafupifupi 82,000 odwala khansa ya endometrial adanenedwa ku China, ndipo pafupifupi 16,000 afa.Akuti pofika 2035, padzakhala 93,000 odwala khansa ya endometrial ku China.
Chiwopsezo cha khansa ya endometrial yoyambirira ndi yayikulu kwambiri, ndipo moyo wazaka 5 umakhala mpaka 95%.Komabe, zaka 5 zopulumuka khansa ya endometrial siteji IV ndi 19% yokha.
Khansara ya endometrial imapezeka kwambiri mwa amayi omwe ali ndi vuto lotha msinkhu komanso okalamba, omwe amayamba zaka pafupifupi 55.Komabe, m’zaka zaposachedwapa, pakhala pali chizoloŵezi chowonjezereka cha kansa ya endometrial pakati pa amayi azaka zapakati pa 40 ndi pansi.
Pakali pano palibe njira yoyenera yowunikira khansa ya endometrial
Kwa amayi a msinkhu wobereka, kuyezetsa msanga ndi kuwongolera panthawi yake khansa ya endometrial kungapangitse kutetezedwa kwa chonde ndikupereka mwayi wokhala ndi moyo wautali.
Komabe, pakadali pano palibe njira zowunikira komanso zolondola zomwe sizingawononge khansa ya endometrial muzochita zamankhwala.Zizindikiro monga kutuluka kwa magazi m'chiberekero ndi kumaliseche koyambirira zimanyalanyazidwa mosavuta, zomwe zimachititsa kuti kuphonyedwe mwayi wozindikira msanga.
Kuwunika koyambirira pogwiritsa ntchito kujambula kwa ultrasound ndi kuyezetsa kwanthawi zonse kwa amayi kumakhala ndi chidwi chochepa.
Kugwiritsiridwa ntchito kwa hysteroscopy ndi pathological biopsy ndizovuta, zokhala ndi mankhwala ochititsa dzanzi kwambiri komanso mtengo wake, ndipo zingayambitse magazi, matenda, ndi kuphulika kwa chiberekero, zomwe zimapangitsa kuti chiwerengero chachikulu cha matenda ophonya, ndipo sichigwiritsidwa ntchito ngati njira yowonetsera nthawi zonse.
Kuyesa kwa endometrial biopsy kungayambitse kusapeza bwino, kutulutsa magazi, matenda, ndi kuphulika kwa chiberekero, zomwe zimapangitsa kuti pakhale kuchuluka kwa matenda osowa.
TAGMe DNA Methylation Detection Kits (qPCR) ya Khansa ya EndometrialIkuyambitsa Era ya Endometrial Cancer Dignosis ndi Chithandizo 2.0
TAGMe DNA Methylation Detection Kits (qPCR) ya Khansa ya Endometrialimatha kukwaniritsa zoperewera za njira zowunikira khansa ya endometrial, kuchepetsa kwambiri kuchuluka kwa matenda ophonya komanso kuthandiza odwala kuzindikira zizindikiro za khansa munthawi yake.
Kuyesa osawona kawiri ndi "golide wovomerezeka" wotsimikizira zaukadaulo komanso mulingo wachipatala womwe Epiprobe wakhala akuutsatira nthawi zonse!
Zotsatira za kuyesedwa kwapawiri zikuwonetsa kuti kwa zitsanzo za khomo lachiberekero, AUC inali 0.86, yeniyeni inali 82.81%, ndipo kukhudzidwa kunali 80.65%;Pazitsanzo za burashi ya chiberekero, AUC inali 0.83, kutsimikizika kwake kunali 95.31%, ndipo kukhudzika kunali 61.29%.
Pazinthu zoyezetsa khansa koyambirira, cholinga chachikulu ndikuwunika anthu omwe ali ndi vuto m'malo mowazindikira.
Kwa zinthu zoyezera khansa koyambirira, poganizira kuti cholinga chogwiritsa ntchito ndikuchepetsa chiopsezo cha matenda komanso kupewa matenda omwe adaphonya momwe kungathekere ndikowona mtima kwambiri kwa omwe adayesedwa.
The negative predictive value ofTAGMe DNA Methylation Detection Kits (qPCR) ya Khansa ya Endometrialndi 99.4%, zomwe zikutanthauza kuti mu chiwerengero cha anthu omwe amalandira zotsatira zoipa, 99.4% ya zotsatira zoipa ndi zoipa zenizeni.Kuthekera kopewera matenda omwe anaphonya ndikwabwino kwambiri, ndipo ambiri mwa ogwiritsa ntchito omwe ali ndi vuto akhoza kukhala otsimikiza kuti safunikira kuwunika movutikira ndi ziwopsezo zazikulu zomwe zaphonya.Ichi ndiye chitetezo chachikulu kwambiri kwa ogwiritsa ntchito.
Kudzifufuza paziwopsezo za khansa ya endometrial.
Ndi kusintha kwa moyo, chiwerengero cha khansa ya endometrial ku China chakhala chikuwonjezeka chaka ndi chaka, ndipo pali chizolowezi kwa odwala achichepere.
Ndiye, ndi anthu amtundu wanji omwe amatha kukhala ndi khansa ya endometrial?
Kawirikawiri, anthu omwe amatha kukhala ndi khansa ya endometrial ali ndi makhalidwe asanu ndi limodzi awa:
- Kudwala kagayidwe kachakudya syndrome: matenda yodziwika ndi kunenepa, makamaka kunenepa kwambiri m`mimba, komanso shuga mkulu magazi, abnormal lipids magazi, kuthamanga kwa magazi, etc., amene amakhudza kwambiri thanzi la thupi;
- Kukondoweza kwa estrogen imodzi kwa nthawi yayitali: kukhudzidwa kwa nthawi yayitali ku kukondoweza kwa estrogen imodzi popanda progesterone yogwirizana kuteteza endometrium;
- Kusamba koyambirira ndi kutha kwa msambo: izi zikutanthauza kuti kuchuluka kwa msambo kumawonjezeka, motero endometrium imakhudzidwa ndi kukondoweza kwa estrogen kwa nthawi yayitali;
- Osabereka ana: pa nthawi ya mimba, mlingo wa progesterone m'thupi ndi wapamwamba, womwe ungateteze endometrium;
- Genetic factor: yodziwika bwino kwambiri ndi Lynch syndrome.Ngati pali achinyamata a khansa ya m'mimba, khansa ya m'mimba, kapena achibale achikazi omwe ali ndi khansa ya ovarian, khansa ya endometrial, ndi zina zotero pakati pa achibale apamtima, ziyenera kudziwidwa ndi uphungu ndi kuunika kwa majini;
- Zizoloŵezi zoipa za moyo: monga kusuta, kusachita masewera olimbitsa thupi, komanso kukonda zakudya zopatsa mphamvu zambiri komanso mafuta ambiri monga tchipisi ta mbatata, zokazinga za ku France, tiyi wamkaka, zakudya zokazinga, makeke a chokoleti, ndi zina zotero, choncho m’pofunika kuchita masewera olimbitsa thupi. zambiri pambuyo kuzidya.
Mutha kudzifananiza ndi mikhalidwe 6 yomwe ili pamwambapa yomwe imatha kukhala ndi khansa ya endometrial, ndipo yesani kuwawongolera momwe mungathere kuti mupewe gwero.
Nthawi yotumiza: May-09-2023